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Publications

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Monitoring warfarin with factors II and X only

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Replacement of traditional prothrombin time monitoring with the new Fiix prothrombin time - A review article.

  • Replacement of traditional prothrombin time monitoring with the new Fiix prothrombin time increases the efficacy of warfarin without increasing bleeding. A review article.

  • Authors: Pall T. Onundarson , Ragnar Palsson, Daniel M. Witt and Brynja R. Gudmundsdottir

  • Thrombosis Journal open access Oct 2021

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Monitoring warfarin with factors II and X only

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Monitoring warfarin with factors II and X only

  • Ignoring instead of chasing after coagulation factor VII during warfarin management; an interrupted time series.

  • Authors: Alma R. Oskarsdottir, Brynja R. Gudmundsdottir, Hulda M. Jensdottir, Bjorn Flygenring, Ragnar Palsson, and Pall T. Onundarson

  • Blood May 30 2021

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Monitoring warfarin with factors II and X only

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Blood podcast released May 20, 2021

  • ​

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Monitoring warfarin with factors II and X only

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A better way to monitor warfarin therapy?

  • Commentery

  • Author: Daniel M. Witt

  • Blood May 30 2021

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The need for an adapted initiation nomogram during Fiix prothrombin time monitoring of warfarin

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The need for an adapted initiation nomogram during Fiix prothrombin time monitoring of warfarin

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Oral anticoagulant monitoring: Are we on the right track?

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Oral anticoagulant monitoring: Are we on the right track?
During warfarin induction, the Fiix-prothrombin time reflects the anticoagulation level better than the standard prothrombin time
During warfarin induction, the Fiix-prothrombin time reflects the anticoagulation level better than the standard prothrombin time

7

During warfarin induction, the Fiix-prothrombin time reflects the anticoagulation level better than the standard prothrombin time

  • Authors: Jonsson PI, Letertre L, Juliusson SJ, Gudmundsdottir BR, Francis CW, Onundarson PT

  • J Thromb Haemost. 2017 jan;15(1):131-139. doi 10.1111/jth.13549. Pub 2016 Nov 30

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Reduced anticoagulation variability in patients on warfarin monitored with Fiix-prothrombin time associates with reduced thromboembolism: The Fiix-trial

  • Authors: Oskarsdottir AR, Gudmundsdottir BR, Indridason OS, Arnar DO, Bjornsson ES, Magnusson MK, Jensdottir HM, Vidarson B, Francis CW, Onundarson PT

  • J Thromb Thrombolysis. 2017 May;43(4):550-561. doi 10.1007/s11239-017-1482-4

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Fiix-prothrombin time monitoring improves warfarin anticoagulation outcome in atrial fibrillation

  • A system review of randomised trials comparing Fiix-warfarin or direct oral anticoagulants to standard PT-warfarin

  • Authors: P.T. Onundarson, D.O. Arnar, S.H. Lund, B.R. Gudmundsdottir, C.W. Francis, O.S. Indridason

  • Version of Record online: 17 July 2016. DOI: 10.111/ijlh.12537

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A single test to assay warfarin, dabigatran, rivaroxaban, apixaban, unfractioned heparin, and enoxaparin in plasma

  • Authors: Letertre LR, Gudmundsdottir BR, Francis CW, Gosselin RC, Skeppholm M, Malmstrom RE, Moll S, Hawes E, Francart S, Onundarson PT

  • J Throm Haemost. 2016 May; 15(5):1043-53. DOI: 10.1111/jth.13300

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3

Laboratory monitoring of warfarin in the era of direct oral anticoagulants (editorial comment)

  • Authors: Lippi G, Favaloro EJ.

  • The Lancet Hematology. 2015;2(6):2

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Fiix-prothrombin time versus standard prothrombin time for monitoring of warfarin anticoagulants: a single centre, double-blind, randomised, non-inventory trial

  • Authors: Páll T Onundarson, Charles W Francis, Olafur S Indridason, David O Arnar, Einar S Bjornsson, Magnus K Mangusson, Sigurdur J Juliusson, Hulda M Jensdottir, Brynjar Vidarsson, Petur S Gunnarsson, Sigrun H Lund, Brynja R Gudmundsdottir

  • The Lancet Hematology. 2015;2(6):9

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1

Critical role of factors II and X during coumarin anticoagulation and their combined measurement with a new Fiix-prothrombin time

  • Authors: Brynja R. Gudmundsdottir, Charles W. Francis, Alexia M. Bjornsdottir, Moa Nellbring, Pall T. Onundarson

  • Thromb Res. 2012;130(4):674-81

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